Holmes talks with the two brothers responsible for Ackk Studios and their new game, Two Brothers.

Jonathan talks with indie game designer Jason Rohrer about his new MMO, The Castle Doctrine.

Holmes delves into the depraved mind of Austin Jorgensen, developer behind the successfully Kickstarter project, LISA the Painful RPG.

Holmes gets inside the mind of the man behind the most realistic soda drinking simulator ever created, Will Brierly.

Holmes talks with Marcus Lindblom about localizing MOTHER 2 into the North American release, Earthbound and the changes the games industry has undergone in three decades.

Indie game designer Kyle Reimergartin keeps Holmes off-balance through the art of deception.

Learn more about Kyle and his games at: http://lazercatz.com

Holmes talks with Kristofor Durrschmidt and Taron Millet, co-founders of Crazy Viking Studios!

Learn more about Crazy Viking Studios on Twitter: http://twitter.com/volgarr

Holmes talks with producer Justin Woodward about his experience in learning to develop games and bring them to market.

Michael Molinari, designer of Soundodger and numerous other games, talks to Holmes about his work and career.

Follow Michael on Twitter: twitter.com/onemrbean

Holmes chats with the effervescent Cristina Vee about her career as a voice actor, including her role as Riven in League of Legends, and her work as the voice director for Skullgirls.

Indie game designer Porpentine talks with Holmes about her work and career, including Armada!

Follow Porpentine on Twitter: http://www.twitter.com/AlienDoveCote

Holmes sits down with artist and designer Holly Pickering, currently hard at work on Ether One

Holmes talks with David S. Gallant about his career and games, including I Get This Call Every Day.

Holmes talks with Shawn Alexander Allen about his career in the games industry, from Rockstar Games to his new project, Treachery in Beatdown City!

Holmes learns about the Earthbound-inspired Citizens of Earth from Eden Industries founder and veteran gameplay programmer Ryan Vandendyck.

Learn more about Citizens of Earth: http://www.kickstarter.com/projects/499609193/citizens-of-earth-a-modern-rpg
Follow Ryan on Twitter: https://twitter.com/EdenIndustries

Holmes talks with freelance writer Leigh Alexander about the current state of the games industry and transcending the mainstream in our search for better games.

Merritt Kopas, designer of Gone Home, talks about her career shift from academia to game design.

Jonathan Holmes sits down with artist Richard Hogg.

Holmes sits down with WayForward co-founder and creator of Shantae, Matt Bozon.

Jonathan Holmes talks with renowned game music composer Jake Kaufman.

Wayfor-gust continues as Holmes welcomes Austin Ivansmith back to the program to discuss the recently released Ducktales Remastered!

Holmes sits down with Jeff Luke, a game director at WayForward currently working on The Regular Show: Mordecai and Rigby in 8-Bit Land.

Holmes talks with artist and game designer Cassandra Chui of Michael Todd Games about the path which has led to her first commercially released game project, Electronic Super Joy.

Holmes talks with Paul Veer, whose pixel creations have appeared in numerous games from Vlambeer, Adam Atomic and more.

Matt Thorson appears on the show to talk about his career and games, which includes indie classics like Jumper, the wildly popular Adult Swim game Give Up, Robot, and OUYA's killer app, Towerfall.

Jools Watsham returns to the program to talk about upcoming games from Renegade Kid (including Cult County and Treasurenauts) and turns the tables on Holmes by taking over the questions portion of the show.

Holmes talks with Michael Frauenhofer, designer of Demon Chic, and learns what it's like when software development becomes a family business.

Holmes sits down with Rich Vreeland, better known as "Disasterpeace," whose music has contributed to the soundtracks of Fez, Shoot Many Robots, KRUNCH, Bit.Trip Runner 2 and many other games.

Holmes is joined by designer and producer Kellee Santiago to discuss her career, including her work as president of thatgamecompany and her new role as a consultant and advisor.

Holmes welcomes James Silva to the show to discuss his career, from the incredibly successful "I MAED A GAM3 W1TH Z0MBIES 1N IT!!!1" and "The Dishwasher: Dead Samurai" through to his latest effort, "Charlie Murder"

Holmes talks with Graham Smith and Chris Morris from Drinkbox Studios

Holmes talks with Rami Ismail and Jan Willem Nijman, the two developers who make up Vlambeer and responsible for Super Crate Box, Ridiculous Fishing and the upcoming Luftrausers!

Holmes speaks with Lone Survivor creator Jasper Byrne about the game's pending arrival on PS3 and PS Vita, as well as his latest project, New Game+

Holmes speaks with Cart Life designer Richard Hofmeier

Holmes speaks with Sean Velasco, Nick Wozniak and Erin Pollson from Yacht Club Games

Holmes talks with Mike and Vieko (aka "LeGrudge & Rugged") about Krunch and a number of upcoming projects.

Holmes speaks with WayForward Director Tomm Hulett about his lengthy career working with Virgin, Atlus and Konami on franchises such as Silent Hill, Shin Megami Tensei and Contra

Jonathan Holmes talks with Adam "Keits" Heart from Iron Galaxy Studios, designer of Divekick.

Jonathan Holmes speaks with Steve Swink, a game designer whose work ranges from developing new forms of educational software to the Tony Hawk franchise, to discuss his career and his current project, Scale.

Holmes talks with independent game designer Paul Greasley.

Holmes talks with Andy Schatz, designer of the IGF award-winning Monaco: What's Yours is Mine.

Holmes talks with Edmund McMillen about the upcoming title from Team Meat, MewGenics.

Holmes talks with Erin Robinson, designer of Puzzle Bots and the forthcoming Gravity Ghost and keynote speaker for the 2013 Global Game Jam.

Holmes talks with Vander Caballero, co-founder of Minority Media and designer of Papo & Yo.

Holmes talks with Austin Ivansmith, director of Mighty Switch Force HD.

Holmes talks with PixelJam co-founders Rich Grillotti and Miles Tillman about the creation of their company, early Flash games and their work with Adult Swim, as well as their current project, Glorkbot Adventures.

Holmes sits down with former Destructoid writer Matthew Walden, who has also written for Geoff Keighley at Gametrailers TV as well as a variety of other television projects, and discuss his experiences with post-traumatic stress disorder and video games.

Holmes talks with Nels Anderson, lead designer of the critically-acclaimed Mark of the Ninja

Holmes sits down with Davey Wreden, creator of The Stanley Parable!

Holmes speaks with Luis Hernandez, co-founder of Necrophone Games, about his upcoming title Jazz Punk

Holmes sits down with Frog Fractions creator Jim Crawford.

Holmes is joined by Beau Blyth (aka Teknopants) to discuss LA Death Disk

Holmes sits down with Gordon Midwood of Different Cloth / Different Tuna, to discuss his games Derrick the Deathfin and Lilt Line.

Jonathan talks with artist and animator Mariel Cartwright about her work on games including Skullgirls, Scott Pilgrim: The Game and Lesbian Spider Queens from Mars.

Jon talks with comic artist and writer James Kochalka, currently working with PixelJam on Glorkbot Adventures!

Holmes talks with George Royer and Jo Lammert of White Whale Games about their iOS release, God of Blades.

Holmes speaks with Douglas Wilson of Die Gute Fabrik, makers of Johann Sebastian Joust and Where is my Heart?

As we conclude WayForwardVember, Holmes chats with Sean Velasco, director of Double Dragon Neon and A Boy and His Blob

Holmes talks with Adam Tierney of WayForward. Topics include Silent Hill: Book of Memories, LIT, Aliens: Infestation and much more

Holmes speaks with James Montagna of WayForward, currently working on Adventure Time: Hey Ice King! Why'd you Steal our Garbage?

Holmes is joined by Dennis Wedin and Jonatan Söderström of Dennaton, developers of Hotline Miami

Holmes speaks with returning guest Tyrone Rodriguez, CEO of Nicalis

Holmes speaks with McPixel designer Sos Sosowski.

Brian Provinciano returns to Sup, Holmes? following the release of Retro City Rampage

Holmes is joined by Alexander Bruce, designer of the IGF Award-winning game Antichamber

Holmes speaks with Derek Yu, designer of Spelunky, Aquaria and many more, and operator of indie games community TIGsource.

Holmes speaks with Zach Gage, designer of Spell Tower and Bit Pilot

Holmes speaks with Sophie Houlden, designer of Swift*stitch

Holmes speaks with indie game designer and 'Rise of the Videogame Zinesters' author, Anna Anthropy.

Holmes speaks with Sound Shapes creators Shaw-Han Liem and Jonathan Mak

Holmes talks with Mike Bithell, designer of minimalist platformer Thomas Was Alone.

Holmes talks with Gearbox Software writer (and former Destructoid Features Editor) Anthony Burch

Holmes talks with Jonathan Blow, designer of Braid and The Witness

Holmes is joined by Deigo Garcia and Emmett Butler, designers of Heads-Up! Hotdogs

Christine Love, developer of Digital: A Love Story and Analogue: A Hate Story, joins Holmes for a rousing discussion of Visual Novels, game design, anime and gender issues.

Holmes is joined by game designer and writer, Tim Rogers

Holmes is joined by indie developer Shawn McGrath, currently working on Dyad for PS3. This episode features an unusual amount of crude langauge. Listener discretion advised.

Holmes is joined by indie developer Damian Sommer, designer of The Clown Who Wanted Everything. http://damiansgames.com

Holmes is joined by Zoe Quinn, developer and co-founder of Dames Making Games

Holmes is joined by Miguel Sternberg, founder of Spooky Squid Games

Holmes is joined by Rami Ismail of Vlambeer, developers of Super Crate Box, Radical Fishing and Serious Sam: The Random Encounter

Holmes is joined by Scott LaGrasta, a level designer at 2K Marin who has worked on a number of big budget titles, including BioShock 2, and a Molyjam contributor.

Holmes is joined by Jasper Byrne, developer of Lone Survivor and Soundless Mountain II.

Holmes is joined by Mike Zaimont, competitive BlazBlue player and lead designer of Skullgirls.

In this episode, Holmes is joined by Anthony Carboni from Revision3 Gaming, host of "A New Challenger." 

Holmes is joined by Renegade Kid co-founder Jools Watsham.

In this episode of Sup, Holmes?, Jonathan is joined by Adam Saltsman, celebrated developer of Canabalt, Gravity Hook and many more. Here he discusses his new game based on "The Hunger Games," and what it's like to developed licensed games. Plus, a discussion on the difference between "art" and "craft" and the perils of success.

In this episode of Sup Holmes?, Holmes is joined by Philip Tibitoski, President of Young Horses. Topics include the upcoming Octodad: Dadliest Catch, surrealism in gaming and what happens when a bunch of developers live in a house, stop being polite and start getting real.

In this full episode of Sup Holmes?, Jonathan's guest is the irrepressible Luc Bernard, developer of Eternity's Child and Mecho Wars. 

Jonathan is joined by Retro City Rampage creator Brian Provinciano for a frank discussion of the challenges in being an indie developer trying to get your game released to the world. Plus, new details on Retro City Rampage.

In the third episode of Sup Holmes?, Destructoid's Jonathan Holmes is joined by Alex Neuse and Mike Roush of Gaijin Games in a discussion about rebirth. Hear the pair's thoughts on why the $0.99 price point is ruining everything, why Mega Man should die and how a Bit.Trip RPG is something they think about all the time.

In our second episode, Holmes is joined for a celebration of life and love by Tommy Refenes of Team Meat and Shannon Gregory. They're lovers and stuff. Topics include romantic games and relationship advice.

The first (technologically challenged) episode of Sup, Holmes? now in audio-only format. Destructoid's Jonathan Holmes is joined by Tyrone Rodriguez, CEO of Nicalis, publisher of Cave Story, VVVVVV and NightSky. Topics include the role of the games press and announcements regarding several of Nicalis' titles.